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What is Meridia?

  • Meridia affects chemicals in the body that are related to weight maintenance.
  • Meridia is used as a short-term supplement to diet and exercise in the treatment of obesity.
  • Meridia may also be used for purposes other than those listed in this medication guide.

How Maridia Works

MERIDIA works by acting on the appetite control center in the brain. Studies have shown that using MERIDIA, along with a reduced-calorie diet and exercise, helped patients lose weight and maintain weight loss for up to two years.

The active ingredient in MERIDIA, sibutramine, works in the area of the brain that signals the sense of fullness (satiety).1 Meridia does not suppress appetite, which is your signal to start eating.

Meridia blocks the re-uptake of the brain chemicals (serotonin and norepinephrine) which help regulate the sense of fullness.1 Fullness is your signal to stop eating. Having a sense of fullness, or satiety, means you may feel satisfied with less food.

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Is MERIDIA Right for You?

MERIDIA is recommended for:

Overweight people with an initial Body Mass Index (BMI) of 30 or higher or Overweight people with a BMI of 27 or higher if they have medical risk factors such as high blood pressure, diabetes, or high cholesterol.

BMI is an indicator of total body fat, which can be related to the risk of certain diseases and premature death. Your doctor can tell you if your BMI meets these criteria and if MERIDIA might be right for you.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

  • Seek emergency medical attention.
  • Symptoms of a Meridia overdose are not known.

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How should I take Meridia?

  • Take Meridia exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
  • Take each dose with a full glass of water.
  • Meridia is usually taken once a day. Follow your doctor's instructions.
  • Meridia can be taken with or without food. • Never take more of this medication than is prescribed for you. Too much Meridia could be dangerous.
  • Meridia has been reported to cause increased blood pressure in some patients. It is important to have your blood pressure and pulse monitored regularly while taking Meridia.
  • Store Meridia at room temperature away from moisture and heat.

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What should I avoid while taking Meridia?

  • Use caution when driving, operating machinery, or performing other hazardous activities. Meridia may cause dizziness, difficulty concentrating, or restlessness. If you experience these effects, avoid hazardous activities.
  • Do not take any other prescription or over-the-counter medicines without first talking to your doctor, especially weight-loss products, tryptophan (L-tryptophan, 5-HTP), decongestants, antidepressants, cough suppressants, lithium (Eskalith, Lithobid, Lithonate, others), and migraine medicines.

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